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Glomerulosclerosis in aging nephropathy. A: glomerulosclerosis, quantitated on PAS-stained sections in aging Ren1cCre × Rs-ZsGreen-R reporter mice, increased significantly at 52 and 64 wk compared with younger ages. B–E: representative images of glomeruli at 4 (B), 12 (C), 52 (F), and 64 wk (G) show decreased podocyte number, glomerulosclerosis, and synchiae (indicated by arrows), features consistent with aging nephropathy.
