Fig. 3.
Cells of renin lineage increase in the intraglomerular compartment and glomerular injury is reduced in glomeruli containing cells of renin lineage in aged Ren1cCre × Rs-ZsGreen-R mice. A–C: representative pictures of kidneys from mice aged 12, 52, and 64 wk. Glomeruli with no labeled cells of renin lineage (CoRL) are indicated by solid circles, glomeruli containing labeled CoRL are indicated by dashed circles. D: quantification of the percentage of glomeruli containing labeled CoRL, percentage of glomeruli with injury, percentage of glomeruli with labeled CoRL with injury, and percentage of glomeruli with no labeled CoRL with injury.