Table 2.
Transport characteristics for NH3 and NH4+ in heterologous expression systems
| Rhbg | |||||
|---|---|---|---|---|---|
| Electroneutral |
Electrogenic |
||||
| Expression system | NH3 transport | CH3NH2 transport | NH4+ transport | CH3NH3+ transport | Citation, Year |
| Murine Rhbg expressed in Xenopus oocyte | Absent | Present | (78), 2004 | ||
| Human RhBG in Xenopus oocyte | Present | Absent | (64), 2004 | ||
| Human RhBG in HEK293 and MDCK cells | Present | Absent | (114), 2005 | ||
| Murine Rhbg | Present | Absent | (66), 2006 | ||
| Murine Rhbg in Xenopus oocyte | Present | Present | Present | (76), 2010 | |
| Murine Rhbg in Xenopus oocyte | Absent | Present | Present | Present | (77), 2010 |
| Human RhBG in Xenopus oocyte | Present | (25), 2013 | |||
| Rhcg | |||||
| Human RhCG expressed in Xenopus oocyte | Present | Present | (7), 2004 | ||
| Human RhCG in HEK293 and MDCK cells | Present | Absent | (114), 2005 | ||
| Murine Rhcg in Xenopus oocyte | Present | Absent | (66), 2006 | ||
| Human RhCG in Xenopus oocyte and in S. cerevisiae | Present | Absent | (71), 2006 | ||
| Rhcg gene deletion, perfused collecting duct segment, apical transport | Present | Absent | (10), 2008 | ||
| Purified RhCG-HA reconstituted in liposomes | Present | Absent | (74), 2010 | ||
| Human RhCG reconstituted in liposomes | Present | Absent | (26), 2010 | ||
| Rhcg gene deletion, perfused collecting duct segment, basolateral transport | Present | Absent | (11), 2012 | ||
| Human RhCG in Xenopus oocyte | Present | (25), 2013 | |||
MDCK, Madin-Darby canine kidney; HA, hemagglutinin.
If neither “present” nor “absent” is noted for a specific transport modality, then that transport modality was not explicitly examined.