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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Acta Biomater. 2013 Aug 2;9(12):9292–9302. doi: 10.1016/j.actbio.2013.07.032

Figure 6.

Figure 6

Effect of HA-o released from NPs on MMP-2 synthesis in EaRASMC cultures, as analyzed with Western blots. (A) Representative image of Western blot, with β-actin bands as loading controls. (B) Fold change in production of active MMP-2 compared to control cultures without NPs. Data represented as mean ± SD; n = 3 per case * denotes p < 0.05 compared to controls with no NPs. Note: the values in (B) represent the fold change in normalized band intensities of the active MMP-2 band for each treatment test case (normalized to its corresponding β-actin loading control band to enable accurate comparison between the different test cases) compared to untreated (no NP) controls. The normalized band intensity of MMP-2 for the NP-untreated control test condition was set to unity to determine the fold change in MMP-2 expression or activity for the different NP-treated test cases.