FIG. 6.

EBRT increases expression of cell surface immunostimulatory proteins and decreases expression of cell surface immunoinhibitory proteins leading to activation of CTLs and IFN-γ production. Untreated PCa cells display low levels of stimulatory proteins (green) and high levels of inhibitory proteins (red). After treatment with EBRT, PCa cells increased their expression of stimulatory proteins (green) and decreased their expression of inhibitory proteins (red), thereby, preferentially activating CTL-mediated cell killing and production of IFN-γ.