Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 28;111(19):E2008–E2017. doi: 10.1073/pnas.1402944111

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 5. — DRG from GFRα1^+/− mice attract less cancer cell migration and less PNI compared with DRG from wild-type GFRα1^+/+ mice. (A) Protein isolated from lysed DRG from GFRα1^+/− and GFRα1^+/+ mice underwent Western blotting for GFRα1. (B) The migration of MiaPaCa-2 shGFRα1 in Boyden chamber assays was quantified using GFRα1^+/− DRG or GFRα1^+/+ DRG as an attractant (^†P < 0.001; t test). (C) DRG coculture assays were performed using MiaPaCa-2 shGFRα1 cells. Greater PNI was noted with GFRα1^+/+ DRG compared with GFRα1^+/− DRG. (D) The average area of invasion by MiaPaCa-2 shGFRα1 cells in DRG assays using GFRα1^+/− DRG compared with GFRα1^+/+ DRG (^††P < 0.05; t test).