Table 3.
Clinical characteristics of the overall sample (n = 1,305) used for primary ICA analysis
| Clinical characteristic | Controls (n = 324) | SZ probands (n = 296) | PBP probands (n = 300) | SZREL (n = 179) | BPREL (n = 206) | Statistic | P value | |||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | F | ||
| Age, y | 35.2 | 13.4 | 34.9 | 12.2 | 36.7 | 12.6 | 43.8 | 15.8 | 39.8 | 16.1 | 15.8 | <<0.001 |
| Clinical scores | ||||||||||||
| YMRS | 0.3 | 1.1 | 5.1 | 5.7 | 6.4 | 6.3 | 0.3 | 1.4 | 0.3 | 1.4 | 212.2 | <<0.001 |
| MADRS | 0.3 | 1.5 | 8.7 | 8.3 | 11.6 | 9.8 | 0.8 | 2.8 | 0.7 | 3.0 | 160.1 | <<0.001 |
| SFS | 154.0 | 19.3 | 99.1 | 52.52 | 102.6 | 56.6 | 149.1 | 19.3 | 149.6 | 22.6 | 92.6 | <<0.001 |
| PANSS_POS | N/A | N/A | 16.3 | 5.3 | 15.1 | 5.5 | N/A | N/A | N/A | N/A | N/A | N/A |
| PANSS_NEG | N/A | N/A | 15.8 | 5.5 | 13.1 | 4.6 | N/A | N/A | N/A | N/A | N/A | N/A |
| SBS | N/A | N/A | 7.6 | 1.3 | 2.5 | 1.9 | N/A | N/A | N/A | N/A | N/A | N/A |
For medication information on subjects please refer to Table S3. MADRS, Montgomery-Asberg Depression Rating Scale; PANSS: Positive and Negative Symptom Scale; SBS: Schizo-Bipolar Scale; SFS: Social Functioning Scale; YMRS, Young Mania Rating Scale.