Table 2.
Patient characteristic | MMX mesalazine (n = 4,751) | All comparators (n = 10,176) | Total (n = 14,936) |
---|---|---|---|
Mean age (median), years | 44.38 (44.0) | 47.44 (47.0) | 46.46 (46.0) |
Age categories, n (%) | |||
18–19 | 130 (2.7) | 187 (1.8) | 318 (2.1) |
20–29 | 740 (15.6) | 1,367 (13.4) | 2,108 (14.1) |
30–39 | 1,031 (21.7) | 1,829 (18.0) | 2,862 (19.2) |
40–49 | 1,075 (22.6) | 2,172 (21.3) | 3,249 (21.8) |
50–59 | 1,013 (21.3) | 2,307 (22.7) | 3,322 (22.2) |
60–69 | 532 (11.2) | 1,451 (14.3) | 1,984 (13.3) |
70–79 | 164 (3.5) | 534 (5.2) | 698 (4.7) |
≥80 | 66 (1.4) | 329 (3.2) | 395 (2.6) |
Gender, n (%) | |||
Female | 2,528 (53.2) | 5,527 (54.3) | 8,060 (54.0) |
Male | 2,223 (46.8) | 4,649 (45.7) | 6,876 (46.0) |
Index date, n (%) | |||
Year 2008 | 1,589 (33.4) | 3,958 (38.9) | 5,549 (37.2) |
Year 2009 | 1,953 (41.1) | 3,608 (35.5) | 5,566 (37.3) |
Year 2010 | 1,209 (25.4) | 2,610 (25.6) | 3,821 (25.6) |
Common baseline pharmacotherapy (>10% of patients), n (%) | |||
Acetaminophen | 904 (19.0) | 2,106 (20.7) | 3,010 (20.2) |
Potassium chloride | 1,049 (22.1) | 1,827 (18.0) | 2,877 (19.3) |
Hydrocodone | 650 (13.7) | 1,596 (15.7) | 2,246 (15.0) |
Metronidazole | 627 (13.2) | 1,536 (15.1) | 2,165 (14.5) |
Other mesalazine | 857 (18.0) | 1,035 (10.2) | 1,893 (12.7) |
Ciprofloxacin | 546 (11.5) | 1,290 (12.7) | 1,839 (12.3) |
Sodium bicarbonate | 560 (11.8) | 948 (9.3) | 1,508 (10.1) |
Common pre-index medical conditions (>10% of patients), n (%) | |||
Gastrointestinal inflammation | 1,851 (39.0) | 4,035 (39.7) | 5,891 (39.4) |
Diarrhoea | 1,559 (32.8) | 3,353 (33.0) | 4,913 (32.9) |
Abdominal pain | 1,110 (23.4) | 2,797 (27.5) | 3,910 (26.2) |
Rectal hemorrhage | 1,111 (23.4) | 2,131 (20.9) | 3,245 (21.7) |
Essential hypertension | 742 (15.6) | 2,047 (20.1) | 2,790 (18.7) |
Hematochezia | 866 (18.2) | 1,666 (16.4) | 2,534 (17.0) |
Gastrointestinal disorder | 584 (12.3) | 1,107 (10.9) | 1,691 (11.3) |
Hyperlipidemia | 447 (9.4) | 1,166 (11.5) | 1,613 (10.8) |
Hemorrhoids | 483 (10.2) | 1,007 (9.9) | 1,491 (10.0) |
Benign colonic neoplasm | 485 (10.2) | 976 (9.6) | 1,463 (9.8) |