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. 2014 Mar 11;70(6):709–717. doi: 10.1007/s00228-014-1660-7

Table 2.

Patient demographic and baseline characteristics

Patient characteristic MMX mesalazine (n = 4,751) All comparators (n = 10,176) Total (n = 14,936)
Mean age (median), years 44.38 (44.0) 47.44 (47.0) 46.46 (46.0)
Age categories, n (%)
 18–19 130 (2.7) 187 (1.8) 318 (2.1)
 20–29 740 (15.6) 1,367 (13.4) 2,108 (14.1)
 30–39 1,031 (21.7) 1,829 (18.0) 2,862 (19.2)
 40–49 1,075 (22.6) 2,172 (21.3) 3,249 (21.8)
 50–59 1,013 (21.3) 2,307 (22.7) 3,322 (22.2)
 60–69 532 (11.2) 1,451 (14.3) 1,984 (13.3)
 70–79 164 (3.5) 534 (5.2) 698 (4.7)
 ≥80 66 (1.4) 329 (3.2) 395 (2.6)
Gender, n (%)
 Female 2,528 (53.2) 5,527 (54.3) 8,060 (54.0)
 Male 2,223 (46.8) 4,649 (45.7) 6,876 (46.0)
Index date, n (%)
 Year 2008 1,589 (33.4) 3,958 (38.9) 5,549 (37.2)
 Year 2009 1,953 (41.1) 3,608 (35.5) 5,566 (37.3)
 Year 2010 1,209 (25.4) 2,610 (25.6) 3,821 (25.6)
Common baseline pharmacotherapy (>10% of patients), n (%)
 Acetaminophen 904 (19.0) 2,106 (20.7) 3,010 (20.2)
 Potassium chloride 1,049 (22.1) 1,827 (18.0) 2,877 (19.3)
 Hydrocodone 650 (13.7) 1,596 (15.7) 2,246 (15.0)
 Metronidazole 627 (13.2) 1,536 (15.1) 2,165 (14.5)
 Other mesalazine 857 (18.0) 1,035 (10.2) 1,893 (12.7)
 Ciprofloxacin 546 (11.5) 1,290 (12.7) 1,839 (12.3)
 Sodium bicarbonate 560 (11.8) 948 (9.3) 1,508 (10.1)
Common pre-index medical conditions (>10% of patients), n (%)
 Gastrointestinal inflammation 1,851 (39.0) 4,035 (39.7) 5,891 (39.4)
 Diarrhoea 1,559 (32.8) 3,353 (33.0) 4,913 (32.9)
 Abdominal pain 1,110 (23.4) 2,797 (27.5) 3,910 (26.2)
 Rectal hemorrhage 1,111 (23.4) 2,131 (20.9) 3,245 (21.7)
 Essential hypertension 742 (15.6) 2,047 (20.1) 2,790 (18.7)
 Hematochezia 866 (18.2) 1,666 (16.4) 2,534 (17.0)
 Gastrointestinal disorder 584 (12.3) 1,107 (10.9) 1,691 (11.3)
 Hyperlipidemia 447 (9.4) 1,166 (11.5) 1,613 (10.8)
 Hemorrhoids 483 (10.2) 1,007 (9.9) 1,491 (10.0)
 Benign colonic neoplasm 485 (10.2) 976 (9.6) 1,463 (9.8)