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. 2013 Sep 6;5(1):99–107. doi: 10.1111/jdi.12131

Figure 4.

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Plasma levels of (a) tumor necrosis factor‐α (TNF‐α); (b) epidermal growth factor (EGF); and (c) fibroblast growth fator‐2 (FGF‐2). The concentration of cytokines in plasma was measured using the Milliplex FlexMap 3D method. *< 0.05, **< 0.01, ***< 0.001, vs healthy volunteers (H); $< 0.05 vs type 2 diabetes group (T2DM); #< 0.05 vs type 2 diabetes patients with non‐infected ulceration (DFU). Results are shown as box and whisker charts displaying minimum, maximum, median, upper and lower quartiles. CHPON, Charcot peripheral osteoneuropathy; DFU‐H, type 2 diabetes patients with healed ulceration; DFU‐I, type 2 diabetes patients with infected ulceration.