Table 1. Sample activities/ learning outcomes facilitated with “Allele Freak” feature.

• Contrast spread of dominant vs. recessive advantageous mutations (or loss of dominant vs. recessive detrimental mutations)

• Calculate or verify predicted equilibrium allele frequencies under heterozygote advantage and heterozygote disadvantage

• Contrast effects of genetic drift with varying population sizes

• Identify likelihood of “eventual” fixation of allele via genetic drift and observe that it is predicted by starting allele frequency

• Explore spread/loss of rare beneficial allele in finite population, varying dominance

• Explore effect of inbreeding on speed of loss of detrimental recessive mutation