Table 1.
Association between polymorphisms in TNFAIP3 gene and rheumatoid arthritis in northern Chinese han subjects
| Genotype | Cases (%) | Controls (%) | OR (95% CI) | p value |
|---|---|---|---|---|
| rs2230926 |
|
|
|
|
| TT |
1072(83.8) |
1133(88.5) |
1.00 |
— |
| TG |
200(15.6) |
143(11.2) |
1.48(1.17-1.86) |
0.001 |
| GG |
8(0.6) |
4(0.3) |
2.11(0.64-7.04) |
0.223 |
| TG/GG |
208(16.2) |
147(11.5) |
1.50(1.19-1.88) |
<0.001 |
| rs13207033 |
|
|
|
|
| GG |
1040(81.3) |
1048(81.9) |
1.00 |
— |
| GA |
232(18.1) |
216(16.9) |
1.08(0.88-1.33) |
0.448 |
| AA |
8(0.6) |
16(1.2) |
0.50(0.22-1.18) |
0.115 |
| GA/AA |
240(18.7) |
232(18.1) |
1.04(0.85-1.27) |
0.683 |
| rs10499194 |
|
|
|
|
| CC |
1156(90.3) |
1215(94.9) |
1.00 |
— |
| CT |
120(9.4) |
63(4.9) |
2.00(1.46-2.74) |
<0.001 |
| TT |
4(0.3) |
2(0.2) |
2.10(0.38-11.50) |
0.392 |
| CT/TT | 124(9.7) | 65(5.1) | 2.01(1.47-2.74) | <0.001 |
Data were calculated by unconditional logistic regression.