Table 2.
Polymorphisms in TNFAIP3 gene and risks of rheumatoid arthritis in females
| Genotype | Cases (%) | Controls (%) | OR [95% CI] | p value |
|---|---|---|---|---|
| rs2230926 |
|
|
|
|
| TT |
912(83.8) |
918(88.2) |
1.00 |
|
| TG |
168(15.5) |
119(11.4) |
1.42[1.10-1.83] |
0.006 |
| GG |
8(0.7) |
4(0.4) |
2.01[0.60-6.71] |
0.255 |
| TG/GG |
176(16.2) |
123(11.8) |
1.44[1.12-1.85] |
0.004 |
| rs13207033 |
|
|
|
|
| GG |
904(83.1) |
872(83.8) |
1.00 |
|
| GA |
176(16.2) |
159(15.2) |
1.07[0.85-1.35] |
0.583 |
| AA |
8(0.7) |
10(1.0) |
0.77[0.30-1.96] |
0.587 |
| GA/AA |
184(16.9) |
169(16.2) |
1.05[0.84-1.32] |
0.674 |
| rs10499194 |
|
|
|
|
| CC |
1009(92.7) |
990(94.2) |
1.00 |
|
| CT |
76(7.0) |
49(4.6) |
1.52[1.05-2.20] |
0.026 |
| TT |
3(0.3) |
2(0.2) |
1.47[0.25-8.83] |
0.672 |
| CT/TT | 79(7.3) | 51(4.8) | 1.52[1.06-2.19] | 0.023 |