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. 2014 Apr 30;10(2):54–59. doi: 10.12965/jer.140100

Table 1.

Expression of adiponectin receptors in vascular cells and vasculatures

Species Vascular beds or Cell Line Gender AdipoR (1 or 2) Method used Disease Reference
Mouse (db/db) Coronary arterioles
Aorta
Male 1 (=), 2 (↓)
1 (=), 2 (↓)
WB Type 2 diabetes Zhang et al., 2010
Mouse (db/db) Aorta Male 1 (=), 2(↓) WB Type 2 diabetes Wong et al., 2011
Rat (Brown norway) Retinal ECs Male 1, 2 Immunofluorescence - Lyzogubov et al., 2012
Rat (Wistar) Aorta Male 1 (↓) PCR Type 1 diabetes Guo et al., 2012
Rat (Sprague dawley) Coronary artery VSMCs Male 1 (↓), 2 (↓) PCR Type 1 diabetes Shen et al., 2012
Rat (Sprague dawley) Aorta Male 1 (↓), 2 (↓) WB Insulin resistance (16 wk High-fat diet) Li et al., 2010
Pig Retinal arterioles - 1, 2 Immunohistochemisty - Omae et al., 2013
Human HUVECs - 1, 2 WB - Zheng et al., 2011
Human HUVECs - 1, 2 WB - Zhang et al., 2009
Human Human airway SMCs - 1, 2 PCR - Shin et al., 2008
Human Human aortic ECs - 1, 2 PCR - Tan et al., 2004

db/db, leptin receptor mutated mouse; ECs, endothelial cells; SMCs, smooth muscle cells; VSMCs, vascular SMCs; HUVECs, human umbilical vein endothelial cells; PCR, polymerase chain reaction; WB, western blotting.