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Q89 Rescues the mutant GnRHR[E90K]. Cells were grown, and Q89 was used at different doses to rescue GNRHR. The EC50 for Q89 was determined to be 1.9 nM (●) in the presence of GNRH (500 nM) and had no effect when GNRH was absent (■). The data presented are means±sd of quadruplicate wells (n=4).
