Fig. 1.

Signal enhancement (A and B) and estimated contrast agent concentration (C and D) uptake profiles obtained from blood, CSF, cortical gray matter, deep gray matter and white matter ROIs in 60 stroke patients, 32 with low overall Fazekas ratings (<1.5) and 28 with high overall Fazekas ratings (≥1.5). (A) and (C) are scaled to illustrate the blood signal relative to the other tissues, while (B) and (D) illustrate the tissue signals only. It is clear that any analysis of contrast agent uptake profiles would depend significantly on whether signal enhancement or modeled contrast agent concentration data was used.