Skip to main content
. 2014 Jun 1;20(16):2606–2620. doi: 10.1089/ars.2013.5406

FIG. 2.

FIG. 2.

Ubiquinol-10 decelerated the age-related decline in the expression of genes and proteins related to mitochondrial function. (A) Real-time PCR analyses of Sirt1, Pgc-1α, Sirt3, and Pparα gene expression levels in livers from 2-, 7-, 13-, and 19-month-old SAMP1 mice fed a control or ubiquinol-10-supplemented diet (n=3–5). (B) Western blot analyses of SIRT1, PGC-1α, SIRT3, ERRα, and SOD2 protein expression levels in livers from 2-, 7-, 13-, and 19-month-old SAMP1 mice fed a control or ubiquinol-10-supplemented diet (n=3–5). (C) A typical primary blot of SIRT1, SIRT3, and PGC-1α in liver samples is shown. *p<0.05; **p<0.01; ***p<0.001. ERRα, estrogen-related receptor alpha; PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1α; SOD2, superoxide dismutase 2; PCR, polymerase chain reaction.