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. 2012 Jan 24;3(4):278–283. doi: 10.1021/ml200257n

Table 4. Kinase Selectivity Data for 3a and Related Compounds.

cpd GSK-3β IC50 (μM) HipK2 IC50 (μM) Dyrk1 IC50 (μM) CDK2 IC50 (μM)
3a 0.13 0.03 0.8 26
3b 0.7 0.05 0.02 >30
3c 1.0 0.02 1.7 >30
4e 2.6 0.06 2.6 >30
4g 1.4 <0.003 0.4 >30
5b 0.25 <0.003 0.06 14
5f 6 0.57 5.4 >30