Table 1. Various Heterocyclic Substituted Diazepenes' Human Binding/Functional Activity and Mouse Functional BRS-3 Activity.
Enantiomerically pure compounds unless otherwise noted.
Data expressed as mean ± SD (n ≥ 2 independent experiments).
%Act represents the maximum activation of tested compound relative to that of the known BRS-3 agonist dY peptide compound.