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. 2012 Apr 4;3(5):411–415. doi: 10.1021/ml3000512

Table 2. Rat Enterocyte and Plasma Concentrations of Compound 7 Following a 5 mg/kg Oral Dose.

graphic file with name ml-2012-000512_0001.jpg

time (h) duodenum (nM) jejunum (nM) p. veina (nM) plasma (nM)
2 500 930 22 16
6 630 2020 8 7
17 610 1400 5 BDLb
a

Portal vein.

b

BDL = below detection limit (<3 nM).