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. 2012 Jul 12;3(8):663–667. doi: 10.1021/ml300169x

Table 1. Examples of Substitutions in Adenine-Based LigA Inhibitors Resulting in an Alternative MOA in H. influenzae but Not in S. pneumoniae.

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a

MIC and MOA obtained in the test strain S. pneumoniae SPN100 and H. influenzae HIN101; MOA via LigA (+) or via another yet undetermined target (−).