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. 2012 Jan 25;3(3):187–192. doi: 10.1021/ml200204m

Table 3. Rat Fractions Unbound and Plasma, Brain, and CSF Exposure for 7.

fraction unbound
 concna (nM)
brain plasma free plasma free brain CSF
39.3 89.3 10200 ± 403 3760 ± 776 4060 ± 969
a

Drug concentrations measured at 0.25 h time point, 10 mg/kg sc dose.