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. Author manuscript; available in PMC: 2014 May 19.
Published in final edited form as: Ann Surg Oncol. 2013 Jun 28;20(11):3484–3490. doi: 10.1245/s10434-013-3076-5

Table 2.

Histopathologic Findings of Bethesda Categories III/IV vs. V/VI

Bethesda Category
N=360 III or IV (n=73) V or VI (n=287) p-value
Tumor size (cm)1 1.5 (0.5–8.0) 1.3 (0.2–11.0) 0.025
Extrathyroidal extension 12 (16%) 87 (30%) 0.018
Lymphovascular invasion 14 (19%) 39 (14%) 0.229
Multifocal 27 (37%) 147 (51%) 0.030
Positive margins 4 (6%) 35 (12%) 0.105
Suspicious lymph nodes (if CND performed) 4 (36%) 34 (14%) 0.037
Lymph node metastases2 9 (31%) 129 (50%) 0.053
% Positive lymph nodes 15/106 (14%) 520/2269 (23%) 0.035
# lymph nodes sampled1 0 (0–14) 7 (0–33) <0.001
1

Median (range).

2

Percentages reflect only patients who had lymph nodes sampled.

CND = central compartment lymph node dissection.