Table 2.
Test compounds | Concentration μM | Glutamate uptake dpm | %Control |
---|---|---|---|
None | 247,286 | 100 | |
Brilliant Yellow | 50 | 279,032 | 112 |
Direct Violet 51 | 50 | 258,020 | 104 |
Synaptosomes were incubated with [3H]glutamate in the absence or presence of 50 μM test agent in a Krebs-Ringer solution, as described in Materials and Methods. Na+-dependent [3H]glutamate uptake into synaptosomes is presented.