Fig. 2. K-RasG12V transformation affects KIF2C expression more than loss of p53.
(A) KIF2C and KIF2A were immunoblotted in HBEC3KTRL53 following depletion of K-Ras with siRNA compared to a non-targeting control siRNA. (B) KIF2C was immunoblotted in HBEC30KT following depletion of p53 with siRNA compared to non-targeting control siRNA. (C) KIF2C was immunoblotted in lysates of HBEC3KTRL53 or (D) KIF2A was immunoblotted in HBEC3KT and H358 in each case following re-expression of p53.