Figure 1.
(A) Schematic diagram of Gleevec. (B) Pairwise percentage of sequence identity of Abl, c-Kit, Lck, and c-Src based on multiple sequence alignment of Clustalw2 program. (C) Superimposing the conformation of Gleevec bound to the kinase domains of Abl (colored in red), c-Kit (in orange), Lck (in green), and c-Src (in blue). Gleevec is represented by thick sticks.