Differential electrostatic (Eelec) interaction energies (in kcal/mol) between each individual kinase residue and Gleevec in c-Kit (in color of orange), Lck (in color of green), and c-Src (in color of blue) relative to the corresponding residue in Abl. In each text box, Abl residue is at the bottom and the corresponding c-Kit/Lck/c-Src residue is on the top. The actual ΔEelec of water in Lck, which is 16.4 kcal/mol, is truncated for the consideration of figure resolution.