Table 1. Survival distribution in mice treated with rapamycin and solvent (control) from different age.
| Group | Age at start, mo | Age of mice, months | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ||
| Control-2 | 2 | 12 | 12 | 12 | 11 | 11 | 10 | 9 | 8 | 3 | 1 | 0 | 0 |
| Rapamycin-2 | 2 | 11 | 11 | 10 | 9 | 9 | 8 | 8 | 7 | 5 | 3 | 1 | 0 |
| Control-4 | 4 | - | - | 32 | 32 | 32 | 31 | 29 | 22 | 6 | 2 | 0 | 0 |
| Rapamycin-4 | 4 | - | - | 32 | 32 | 32 | 32 | 30 | 27a | 13a | 3 | 0 | 0 |
| Control-5 | 5 | - | - | - | 19 | 19 | 19 | 19 | 13 | 3 | 1 | 0 | 0 |
| Rapamycin-5 | 5 | - | - | - | 19 | 18 | 18 | 17 | 16a | 12a | 2 | 1 | 0 |
a Significant difference with the corresponding control group: P < 0.01 (Fischer exact test)