Table 2. Parameters of life span in mice treated with rapamycin and solvent (control) from different age.
| Parameters | Control-2 | Rap-2 | Control-4 | Rap-4 | Control-5 | Rap-5 |
|---|---|---|---|---|---|---|
| No. of mice | 12 | 11 | 32 | 32 | 19 | 18 |
| Mean life span, d | 268 ± 15.2 | 272 ± 25.5 | 278 ± 5.4 | 293 ± 4.7 +5.4%; t = 2.09 |
285 ± 5.5 | 304 ± 7.7 +6.7%; t = 2.01 |
| Median life span, d | 282 | 298 | 278 | 295 | 289 | 305 |
| Mean life span of last 10%, d | 333 ± 0 | 365 ± 0 +9.6% | 333 ± 7.3 | 339 ± 3.8 | 331 ± 5.5 | 358 ± 12.5 (+8.2%); t = 1.98 |
| Maximum life span, d | 333 | 365 +9.6% | 340 | 346 | 336 | 370 (+10.1%) |
The difference with relevant controls is significant, P < 0.05.