Table 1.

Exclusion criteria

•  Diabetes mellitus, defined as plasma glucose >126 mg/dL or use of antidiabetic drugs

•  Severe chronic renal insufficiency (GFR < 30 mL/min/1.73 m2 calculated with the MDRD equation)

•  AIDS diagnosis, conditions with short life-expectancy

•  Consumption of design drugs within the last 5 years*

•  Allergy to iodine or gadolinium based contrast agents

•  Claustrophobia

•  Metallic implants (eg pacemakers, defibrilators)

•  Acute psychotic attack

*Design drugs investigated were METH (methamphetamine, also called speed, crystal meth), MDA (3,4- methylenedioxyamphetamine, also known as love drug), MDMA (3,4-methylenedioxy-N-methylamphetamine, also known as ecstasy) and MDEA / MDE (3,4- methylenedioxy –N-ethylamphetamine, also called Eve).