Table 2.
Outcome and monitoring data of patients
| Outcomes | Intermittent sedation (n = 30) | Daily interruption (n = 30) | P- value |
|---|---|---|---|
| Ventilator-free days in 28 days, days |
25 (21, 27) |
24 (0, 26) |
0.160 |
| ICU mortality, n (%) |
7 (23) |
12 (40) |
0.165 |
| Hospital mortality, n (%) |
9 (30) |
13 (43.3) |
0.284 |
| Delirium, n (%) |
12 (40) |
9 (30) |
0.472 |
| Delirium or coma-free days, days |
6 (1,7) |
7 (3, 7) |
0.514 |
| Median SAS |
3.6 (3.4, 4.0) |
3.2 (2.6, 3.7) |
0.035 |
| Percentage of time on target SAS, (%) |
75 (50, 100) |
63 (42, 95) |
0.624 |
| ICU length of stay, days |
11 (6, 16) |
8 (5, 19) |
0.595 |
| Hospital length of stay, days |
22 (13, 38) |
15 (9, 28) |
0.099 |
| Reintubation, n (%) |
1 (3) |
4 (13) |
0.161 |
| Self-extubation, n (%) |
2 (7) |
1 (3) |
0.514 |
| Accidental removal of catheters, n (%) |
1 (3) |
2 (7) |
0.554 |
| Tracheostomy, n (%) |
1 (3) |
1 (3) |
1.000 |
|
Total drug dose per patient |
|
|
|
| Fentanyl, μg |
300 (100, 1,520) |
1,500 (520, 4,215) |
0.004 |
| Midazolam, mg |
0 (0.0,0.5) |
45 (0,201) |
< 0.001 |
| Propofol, mg |
0 (0.0,0.0) |
0 (0.0,0.0) |
0.799 |
| Haloperidol, mg | 0 (0.0,0.0) | 0 (0.0,0.0) | 0.280 |