Table 3.
Data about monitoring, nurses workload, ventilatory and hemodynamic support during the first five days of mechanical ventilation admission
| Ventilatory support | Group | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | P -value |
|---|---|---|---|---|---|---|---|
| Patients alive, n (%) |
Intermittent sedation |
30 (100) |
30 (100) |
28 (93) |
25 (84) |
24 (80) |
0.999 |
| Daily interruption |
30 (100) |
28 (93) |
26 (87) |
25 (84) |
24 (80) |
||
| Patients on mechanical ventilation, n (%) |
Intermittent sedation |
30 (100) |
19 (63) |
17 (61) |
10 (40) |
7 (29) |
0.858 |
| Daily interruption |
30 (100) |
24 (86) |
15 (58) |
12 (48) |
11 (46) |
||
| Pressure support, n (%) |
Intermittent sedation |
28 (93) |
18 (95) |
16 (94) |
10 (100) |
7 (100) |
0.763 |
| Daily interruption |
23 (77) |
20 (84) |
11 (73) |
12 (100) |
9 (82) |
||
| Controlled mode, n (%) |
Intermittent sedation |
2 (7) |
7 (5) |
1 (6) |
0 (0) |
0 (0) |
0.686 |
| Daily interruption |
7 (23) |
4 (16) |
4 (27) |
0 (0) |
2 (18) |
||
|
Hemodynamic support |
|
|
|
|
|
|
|
| Norepinephrine, n (%) |
Intermittent sedation |
18 (60) |
13 (43) |
11 (39) |
2 (8) |
1 (4) |
0.405 |
| Daily interruption |
10 (33) |
6 (21) |
2 (8) |
2 (8) |
2 (8) |
||
| Dobutamine, n (%) |
Intermittent sedation |
13 (43) |
12 (40) |
11 (39) |
7 (28) |
3 (13) |
0.917 |
| Daily interruption |
4 (13) |
4 (14) |
3 (12) |
2 (8) |
0 (0) |
||
|
Monitoring |
|
|
|
|
|
|
|
| Fluid balance, mL |
Intermittent sedation |
935 (323, 2,134) |
960 (421, 2,189) |
−21 (-671, 1,028)d |
237 (-665, 936)d |
−187 (-852, 1,336)d |
< 0.001c |
| Daily interruption |
743 (112, 1,836) |
190 (-705, 1,172)d |
−289 (-1,143, 743)d |
−106 (-804, 849)d |
180 (-1,092, 1,350)d |
0.449b |
|
| Nursing activity scorea |
Intermittent sedation |
54 (49,56) |
48 (45, 52)d |
48 (42, 52)d |
43 (38, 45)d |
39 (34, 46)d |
< 0.001c |
| Daily interruption |
53 (51,54) |
45 (43, 50)d |
45 (40, 52)d |
43 (37, 45)d |
38 (34, 44)d |
0.292b |
|
| Total SOFA score |
Intermittent sedation |
9 (7,12) |
8 (4, 11) |
9 (2, 12) |
7 (2, 10)d |
7 (2, 0)d |
< 0.001c |
| Daily interruption | 7 (4,10) | 7 (4, 10) | 5 (3, 8)d | 4 (3, 9)d | 4 (3, 11)d | 0.545b |
aTime spent for the care of a given patient within a shift.
bMixed model fixed effects-time interaction.
cMixed model fixed effects-group interaction.
dP < 0.05 versus first day.
SOFA, sequential organ failure assessment score.