Table 2.

Effects of Intensive Glycemic Control, Fenofibrate, and Intensive Blood-Pressure Control on Progression of Diabetic Retinopathy and Moderate Vision Loss.^*

Treatment	Progression of Diabetic Retinopathy	Adjusted Odds Ratio (95% CI)	P Value	Moderate Vision Loss	Adjusted Hazard Ratio (95% CI)	P Value
	no./total no. (%)			no./total no. (%)
Glycemia therapy		0.67 (0.51–0.87)	0.003		0.95 (0.80–1.13)	0.56
Intensive	104/1429 (7.3)			266/1629 (16.3)
Standard	149/1427 (10.4)			273/1634 (16.7)
Dyslipidemia therapy†		0.60 (0.42–0.87)	0.006		1.04 (0.83–1.32)	0.73
With fenofibrate	52/806 (6.5)			145/908 (16.0)
With placebo	80/787 (10.2)			136/893 (15.2)
Antihypertensive therapy		1.23 (0.84–1.79)	0.29		1.27 (0.99–1.62)	0.06
Intensive	67/647 (10.4)			145/749 (19.4)
Standard	54/616 (8.8)			113/713 (15.8)

^*Moderate vision loss was defined as loss of visual acuity by three or more lines in either eye.

^†Dyslipidemia therapy consisted of simvastatin plus either fenofibrate or placebo.