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. Author manuscript; available in PMC: 2015 Mar 25.
Published in final edited form as: Circulation. 2014 Jan 7;129(12):1276–1285. doi: 10.1161/CIRCULATIONAHA.113.006611

Figure 1.

Figure 1

Progression of atrial arrhythmia in CREM and CREM:S2814A mice. (A) Representative telemetry ECG recordings revealed the presence of spontaneous atrial ectopy at the age of 3 months and the presence of spontaneous AF (sAF) at the age of 7 months in CREM-mice, whereas no AF was observed in WT or CREM:S2814A mice. (B) left: The number of atrial ectopic events in mice that exhibited sinus rhythm at the age of 3 months. right: The incidence of sAF at the age of 3 months. (C-D) left: The number of atrial ectopic events in mice that exhibited sinus rhythm at the age of 5 and 7 months. middle: The incidence of sAF at the age of 5 and 7 months. right: The duration of longest episodes of sAF at the age of 5 and 7 months. Number in the bars indicated the number of animals studied. *P<0.05, **P<0.01.