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. 2014 May 19;9(5):e97326. doi: 10.1371/journal.pone.0097326

Figure 2. Percentage difference urine chemistry comparisons between wild type (WT) and HYP mice and mice infused with vehicle or SPR4-peptide.

Figure 2

For absolute measurements in tabulated form see Table 2 . Mice were sacrificed on day 28 and urine collected from 16 hour fasted mice housed in metabolic cages. Values are means of percentage difference and are significant (* = P<0.05) unless indicated by NS (unpaired t test confidence, interval  = 95%; see also Table 3 for absolute numbers). Column headings represent; WT  =  wild type mice, HYP  =  X-linked hypophosphatemic rickets mice, SPR4  =  infused SPR4-peptide and Vehicle  =  Saline infused. Histogram bars to the left of zero on the axis indicate down regulation and to the right up regulation. Index : FE Uric Acid  =  percentage change fractional Excretion of uric acid; creatinine clearance  =  percentage change creatinine clearance; ASARM/Cre  =  percentage change in ASARM/creatinine; Ca/Cre  =  percentage change in calcium/creatinine ratio; Fe Ca  =  percentage change in the fractional excretion of calcium; FEP  =  percentage change in the fractional excretion of phosphate; NS  =  not significant; * = P<0.05. Histogram bars to the left of zero on the axis indicate down regulation and to the right up regulation.