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. 2014 May 19;9(5):e97559. doi: 10.1371/journal.pone.0097559

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© 2014 Ogier et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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µCT images of left middle (A–D) and inner (E–H) ears of Chd7^+/+ and Chd7^+/ ^Looper mice. A) Chd7^+/+ and B–D) Chd7^+/ ^Looper malleus (purple), incus (aqua) and stapes (red). The stapes footplate (arrowhead) is fused to the oval window of the cochlea (green) in Chd7^+/ ^Looper mice. E) Chd7^+/+ and F–H) Chd7^+/ ^Looper vestibular apparatus (V) and cochlea (C). The lateral semicircular canal (black arrowhead) is incomplete and the posterior and anterior canals (red arrowheads) are hypoplastic in Cdh7^+/ ^Looper mice. The missing section in each cochlea (*) was an artifact of the imaging/reconstruction process. n = 1 Chd7^+/+ and 3 Chd7^+/ ^Looper mice.