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. Author manuscript; available in PMC: 2014 May 31.
Published in final edited form as: Science. 2013 May 31;340(6136):1232910. doi: 10.1126/science.1232910

Figure 1. Reverse engineering of vaccines.

Figure 1

Figure 1

The figure schematically depicts the identification of bnAbs; technological advances in high-throughput robotic crystallization platforms to enable greater precision in identifying the epitope targets for bnAbs; computational methods to design scaffolds mimicking the binding site of the bnAbs; and lastly greater understanding at the mechanistic level for selection of adjuvants to include in vaccine formulations for potentiating immune responses.