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. Author manuscript; available in PMC: 2014 Dec 26.
Published in final edited form as: J Am Chem Soc. 2013 Dec 12;135(51):19099–19102. doi: 10.1021/ja410902j

Figure 3.

Figure 3

TBP detection on a patterned surface. Current increases negatively down the y-axis. The surface was patterned with four alternating strips of DNA that either lack or contain a TBP binding site. The blue trace is a scan in 2 μM methylene blue and 200 μM ferricyanide before the addition of TBP but after a 30 minute incubation in 100 μM BSA, which controls for non-specific protein binding. The red trace is after a 15-minute incubation with 15 nM TBP protein; the current corresponding to the TBP-binding sequences was diminished, while the current at locations without the protein binding site were unaffected.