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. Author manuscript; available in PMC: 2014 May 19.
Published in final edited form as: Cancer Res. 2010 Jan 1;70(1):388–397. doi: 10.1158/0008-5472.CAN-09-2153

Figure 2.

Figure 2

Purified single-cell s.c. injections into nude mice reveal multiple MPC subsets. A, representative photographs of nude mice bearing tumors of culture 1445 grown from one CD34+ cell (left), one CD34−p75− cell (middle), and a mouse without tumors from p75+ cell injections (right). B, tumor growth over time revealed that CD34+ cells propagated tumors significantly faster than CD34−p75− tumors in all three melanomas. Two tumors that formed from p75+ single-cell inoculations in culture 1118 grew significantly more slowly compared with all other subsets. *, P < 0.05, unpaired Student’s t test, CD34+ versus CD34−p75−; **, P < 0.005, unpaired Student’s t test, CD34+ versus CD34−p75−; #, P < 0.05, unpaired Student’s t test, CD34−p75− versus p75+.