FIG. 3.

Analysis of cell line specific siRNA activity. (A) Expression level of five genes in A549 and SK-N-SH cell lines. Copy number of each gene cDNA was analyzed and presented as described in Fig. 1B. (B) Activities of five siRNAs in A549 and SK-N-SH cell lines. siRNAs targeting each gene were transfected and target mRNA levels were analyzed as described in Fig. 1A. All data in the graphs represent mean±SD values of three independent samples. Student's t-test was used to compare target mRNA knockdown efficiency between two cell lines. *P<0.01; **P<0.05.