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Potential pediatric migraine preventative medications and weight considerations
| Drug class/drug | Weight change |
|---|---|
| Anti-depressants | |
| amitriptyline | ↑ ↑ ↑ |
| nortriptyline | ↑ ↑ |
| protriptyline | ↓ |
| venlafaxine | ↔ ↓ |
| duloxetine | ↔ ↓ |
| Anti-convulsants | |
| divalproex sodium | ↑ ↑ ↑ |
| lamotrigine | ↔ |
| gabapentin | ↑ |
| topiramate | ↓ ↓ |
| β-Blockers | |
| propranolol | ↑ |
| nadololol | ↔ |
| metoprolol | ↑ |
| Serotonin antagonists | |
| cyproheptadine | ↑ ↑ ↑ |
| Calcium channel blockers | |
| flunarizine | ↑ ↑ ↑ |
| verapamil | ↔ |
Modified based on Peterlin et al. 2008 [51].
