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. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: J Clin Monit Comput. 2013 Nov 19;28(4):329–339. doi: 10.1007/s10877-013-9530-x

Model predictions with and without HeRO score, for non-cases (panel A) and cases (panel B). Consistent with the probability densities in Figure 4, there is reduction in predicted risk for non-cases when the HeRO score is added. (Panel C). Dependence of the continuous NRI(>x) on the change in HeRO score required for reclassification. More stringent requirements reduced not only the number of reclassified measurements (right-axis, gray steps) but also the NRI (left-axis, solid line and dashed 95% CI).

Model predictions with and without HeRO score, for non-cases (panel A) and cases (panel B). Consistent with the probability densities in Figure 4, there is reduction in predicted risk for non-cases when the HeRO score is added. (Panel C). Dependence of the continuous NRI(>x) on the change in HeRO score required for reclassification. More stringent requirements reduced not only the number of reclassified measurements (right-axis, gray steps) but also the NRI (left-axis, solid line and dashed 95% CI).