Table 2.

Adverse Events Associated With rhGH Use^a

Organ System/Effect	Severity
Cardiovascular
Cardiomyopathy	++
Heart failure	+
Hypertension	+
Metabolic: diabetes	++
Dermatologic
Excessive seating	+
Coarsening of skin	+
Musculoskeletal
Acral enlargement	+
Carpal tunnel syndrome	+
Osteoarthritis	+
Other: increased risk of cancers	+/−

^aSeverity is scored as follows: ++, well-recognized and probably of serious concern; +, well-recognized but either less common or causing less serious morbidity; +/−, possible risks whose relation to AAS use remains poorly understood.