FIG. 6.
Comparison of analyses of mRNA expression values for cancer versus normal samples of NOX4, DUOX1 and DUOX2 obtained from the Oncomine database. The hydrogen peroxide converting members of the NOX/DUOX family are profiled, with the number of analyses of cancer versus normal tissue demonstrating significant gene upregulation (red) or downregulation (blue) out of total analyses (black) that met the threshold criteria shown across 10 cancer types. One analysis set for DUOX1 expression in lung adenocarcinoma tissue is highlighted [215800_at, (52)], which demonstrates the downregulation of DUOX1 in lung adenocarcinoma.