FIG. 9.

Lung injury in LPS/hyperoxia-exposed mice. Adult mice were treated with a single intraperitoneal injection of saline, 25 mg/kg ATG, and/or 800 mg/kg BSO at 12 h after intratracheal LPS administration. Mice were then exposed to hyperoxia and were sacrificed at 72 h. (A) Representative lung histology (H&E) sections. (B) Standardized lung histology score calculated as described in the Materials and Methods section. Data (mean±SD) were analyzed by one-way ANOVA with Tukey's multiple-comparisons test post hoc (n=3–4). *p=0.012 versus saline. H&E, hematoxylin and eosin. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars