Table 1.
Gene_chr-band | SNPs | bp | Alleles | MA | MAF | p for Hardy–Weinberg equilibrium* | OR | 95 % CI |
---|---|---|---|---|---|---|---|---|
CLU_8p21.1 | rs11136000 | 27,520,436 | C/T | T | 0.4 | 0.84 | 0.86 | 0.81–0.90 |
CR1_1q32.2 | rs3818361 | 205,758,672 | G/A | A | 0.2 | 0.77 | 1.21 | 1.14–1.29 |
PICALM_11q14.2 | rs3851179 | 85,546,288 | C/T | T | 0.37 | 0.12 | 0.86 | 0.81–0.92 |
The PREDIMED-NAVARRA cognitive study
SNP single nucleotide polymorphisms, bp base pair physical position from the March 2006 human reference sequence (NCBI Build 36.1) produced by the International Human Genome Sequencing Consortium, MA allele with the minimum frequency, MAF minimum allele frequency, OR odd ratios, 95 % CI 95 % confidence interval
* Chi-square test for testing the Hardy–Weinberg equilibrium in the PREDIMED-NAVARRA study population