Table 2.
Baseline characteristics of the participants according to intervention group
| MedDiet + EVOO | MedDiet + nuts | Control (low-fat diet) | |
|---|---|---|---|
| n | 220 | 161 | 129 |
| Male (%) | 46 | 42 | 45 |
| Age at baseline (years) | 67 (6) | 67 (6) | 67 (6) |
| Hypertension (%) | 77.3 | 82.6 | 81.4 |
| Dyslipidemia (%) | 70.5 | 69.6 | 66.7 |
| Diabetes (%) | 37.7 | 36.0 | 27.1 |
| ApoE4 genotype (%) | 13.6 | 15.1 | 15.6 |
| CLU (rs11136000) MAF (%) | 0.37 | 0.37 | 0.39 |
| CR1 (rs3818361) MAF (%) | 0.17 | 0.11 | 0.14 |
| PICALM (3851179) MAF (%) | 0.39 | 0.30 | 0.34 |
| Education (years) | 8.5 (2.8) | 8.4 (2.9) | 8.5 (3.4) |
| Family history of cognitive decline (%) | 15.9 | 13.04 | 14.7 |
| Body mass index (kg/m2) | 29.3 (3.4) | 28.9 (3.2) | 29.0 (3.4) |
| Physical activity (MET-min/day) | 283 (199) | 279 (196) | 252 (198) |
| Smoking status (%) | |||
| Current smoker | 15 | 12 | 19 |
| Former smoker | 21 | 22 | 22 |
| Energy intake (kcal/d) | 2,272 (538) | 2,263 (490) | 2,190 (516) |
| Alcohol intake (g/day) | 14 (21) | 13 (18) | 11 (18) |
| MedDiet Score | 9.3 (1.8) | 9.5 (1.8) | 8.6 (1.9) |
Data are shown as mean (SD) unless otherwise stated
The PREDIMED-NAVARRA trial
MAF minor allele frequency, MedDiet Score Mediterranean diet score