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Changes in body weight (a) and adipose tissue mass of 14-week DIO mice, followed by a 5-week diet intervention of ad libitum high-fat diet (40 en% fat, HFD), ad libitum low-fat diet (10 en% fat, LFD), or restricted high-fat diet (30 % restriction of HFD, HFD-CR). b, c Represent white adipose tissue mass of epididymal (b) and peri-renal (c) origin immediately post mortem. Data are mean ± SEM (n = 12). ***p < 0.001
