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Gene expression profiling after a 5-week diet intervention of high-fat ad libitum diet (40 en% fat, HFD), low-fat ad libitum (10 en% fat, LFD), or high-fat restriction (30 % restriction of HFD, HFD-CR) as measured by qRT-PCR on selected target genes. a Mitochondrial biogenesis (Esrra, Ppargc1a), b mitochondrial carbohydrate metabolism (Mpc1, Mpc2, Pdha1, Pdhb, and Pdk1), c fatty acid metabolism (Cpt1a, Cpt1b, and Fasn), d lipolysis (Lipe and Pnpla2), e and inflammation (S100a8)
