Table 1. Candidate genes included in the global omnibus ANOVA.
Gene | Hardy-Weinberg equilibrium (n = 129) | Polymorphism | N (frequency)1 |
ADCY8 | X 2 = 1.72, p = 0.19 | A/A | 11 (13%) |
(rs263249) | A/G | 40 (48%) | |
G/G | 32 (38%) | ||
APOE | X 2 = 3.06, p = 0.08 (rs7412) | ε2 carriers | 19 (23%) |
(rs7412 & | X 2 = 1.32, p = 0.25 (rs429358) | ε3/ε3 | 41 (49%) |
rs429358) | ε4 carriers | 18 (21%) | |
BDNF | X 2 = 2.98, p = 0.08 | A/A | 1 (1%) |
(rs6265) | A/G | 28 (33%) | |
G/G | 55 (66%) | ||
COMT | X 2 = 0, p = 0.98 | A/A | 23 (27%) |
(rs4680) | A/G | 42 (50%) | |
G/G | 19 (23%) | ||
KIBRA | X 2 = 0.97, p = 0.32 | C/C | 35 (42%) |
(rs17070145) | C/T | 38 (45%) | |
T/T | 7 (8%) | ||
PRKACG | X 2 = 0.49, p = 0.48 | C/C | 58 (69%) |
(rs3730386) | C/G | 24 (29%) | |
G/G | 2 (2%) | ||
PRKCA | X 2 = 0.51, p = 0.47 | A/A | 4 (5%) |
(rs8074995) | A/G | 20 (24%) | |
G/G | 58 (69%) |
Only variants with n>16 were analysed, with variants not included in the analysis presented in italic, and variants collapsed into a single carrier group presented in bold.