Table 1.
Characteristics of Experienced Warfarin Users with and Without Mental Health Conditions During Fiscal Years 2007–2008 in the Veterans Health Administration (N = 103,897)
| Variables | With any mental health condition N = 28,216 (%) | No mental health conditions N = 75,681 (%) |
|---|---|---|
| Female gender | 881 (3.1) | 1,095 (1.4) |
| Age group | ||
| 20–54 | 3,395 (12.0) | 3,957 (5.2) |
| 55–59 | 5,327 (18.9) | 6,156 (8.1) |
| 60–64 | 4,493 (15.9) | 8,174 (10.8) |
| 65–69 | 2,756 (9.8) | 8,885 (11.7) |
| 70–74 | 3,416 (12.1) | 13,546 (17.9) |
| 75+ | 8,829 (31.3) | 34,963 (46.2) |
| Race/ethnicity | ||
| Non-Hispanic white | 23,666 (83.9) | 64,815 (85.6) |
| Non-Hispanic black | 2,827 (10.0) | 6,745 (8.9) |
| Others | 1,723 (6.1) | 4,121 (5.4) |
| Primary indication for warfarin* | ||
| Atrial fibrillation | 15,801 (56.0) | 50,955 (67.3) |
| Venous thromboembolism | 9,990 (35.4) | 18,360 (24.3) |
| All others combined | 2,425 (8.6) | 6,366 (8.4) |
| Time since warfarin inception | ||
| ≥6 months before study inception | 19,815 (70.2) | 57,343 (75.8) |
| 6 months before study: First year of study | 7,111 (25.2) | 15,541 (20.5) |
| Second year of study | 1,290 (4.6) | 2,797 (3.7) |
| Comorbid conditions | ||
| Alcohol abuse | 4,818 (17.1) | 4,765 (6.3) |
| Cancer (newly diagnosed) | 2,039 (7.2) | 4,994 (6.6) |
| Chronic kidney disease | 4,102 (14.5) | 10,479 (13.8) |
| Chronic liver disease | 466 (1.7) | 762 (1.0) |
| Chronic lung disease | 10,134 (35.9) | 20,177 (26.7) |
| Dementia | 2,615 (9.3) | 2,876 (3.8) |
| Diabetes | 11,926 (42.3) | 29,581 (39.1) |
| Epilepsy | 1,313 (4.7) | 1,590 (2.1) |
| Heart failure | 9,768 (34.6) | 23,959 (31.7) |
| Hypertension | 20,948 (74.2) | 54,916 (72.6) |
| Stroke | 6,147 (21.8) | 14,229 (18.8) |
| Substance abuse (non-alcohol) | 2,766 (9.8) | 1,398 (1.8) |
| Mean no. (SD) of non- warfarin medications | 11.3 (4.9) | 8.1 (4.2) |
p < 0.001 for all comparisons (t-test and chi-square) *Patients with valvular heart disease or mechanical heart valves were excluded